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The drug hunters : the improbable quest to discover new medicines / Donald R. Kirsch, PhD and Ogi Ogas, PhD.

By: Contributor(s): Material type: TextTextPublisher: New York : Arcade Publishing, [2017]Edition: First editionDescription: 318 pages : illustrations ; 22 cmContent type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
ISBN:
  • 9781628727180
  • 1628727187
Subject(s):
Contents:
Introduction: Searching the library of Babel -- So easy a caveman can do it: the unlikely origins of drug hunting -- Countess Chinchón's cure: the library of botanical medicine -- Standard Oil and standard ether: the library of industrial medicine -- Indigo, crimson, and violet: the library of synthetic medicine -- The magic bullet: we figure out how drugs actually work -- Medicine that kills: the tragic birth of drug regulation -- The official manual of drug hunting: pharmacology becomes a science -- Beyond Salvarsan: the library of dirty medicine -- The pig elixir: the library of genetic medicine -- From blue death to beta blockers: the library of epidemiological medicine -- The pill: drug hunters striking gold outside of Big Pharma -- Mystery cures: discovering drugs through blind luck -- Conclusion: The future of the drug hunter: the Chevy Volt and the Lone Ranger.
Summary: "The surprising, behind-the-scenes story of how our medicines are discovered, told by a veteran drug hunter. The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity-- by chewing, brewing, and snorting--some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Otzi the Iceman, the five-thousand-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze-age medicine, a worm-killing birch fungus, knotted to his leggings. Nowadays, Big Pharma conglomerates spend billions of dollars on state-of the art laboratories staffed by PhDs to discover blockbuster drugs. Yet, despite our best efforts to engineer cures, luck, trial-and-error, risk, and ingenuity are still fundamental to medical discovery. Drug Hunters is a colorful, fact-filled narrative history of the search for new medicines from our Neolithic forebears to the professionals of today, and from quinine and aspirin to Viagra, Prozac, and Lipitor. The chapters offer a lively tour of how new drugs are actually found, the discovery strategies, the mistakes, and the rare successes. Dr. Donald R. Kirsch infuses the book with his own expertise and experiences from thirty-five years of drug hunting, whether searching for life-saving molecules in mudflats by Chesapeake Bay or as a chief science officer and research group leader at major pharmaceutical companies"-- Provided by publisher.
Holdings
Item type Home library Collection Call number Materials specified Status Date due Barcode Item holds
Adult Book Adult Book Main Library NonFiction 615.1072 K61 Available 33111008529782
Total holds: 0

Enhanced descriptions from Syndetics:

The surprising, behind-the-scenes story of how our medicines are discovered, told by a veteran drug hunter.

The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity-- by chewing, brewing, and snorting--some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the five-thousand-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze-age medicine, a worm-killing birch fungus, knotted to his leggings. Nowadays, Big Pharma conglomerates spend billions of dollars on state-of the art laboratories staffed by PhDs to discover blockbuster drugs. Yet, despite our best efforts to engineer cures, luck, trial-and-error, risk, and ingenuity are still fundamental to medical discovery.

The Drug Hunters is a colorful, fact-filled narrative history of the search for new medicines from our Neolithic forebears to the professionals of today, and from quinine and aspirin to Viagra, Prozac, and Lipitor. The chapters offer a lively tour of how new drugs are actually found, the discovery strategies, the mistakes, and the rare successes. Dr. Donald R. Kirsch infuses the book with his own expertise and experiences from thirty-five years of drug hunting, whether searching for life-saving molecules in mudflats by Chesapeake Bay or as a chief science officer and research group leader at major pharmaceutical companies.

Includes bibliographical references (pages 281-301) and index.

Introduction: Searching the library of Babel -- So easy a caveman can do it: the unlikely origins of drug hunting -- Countess Chinchón's cure: the library of botanical medicine -- Standard Oil and standard ether: the library of industrial medicine -- Indigo, crimson, and violet: the library of synthetic medicine -- The magic bullet: we figure out how drugs actually work -- Medicine that kills: the tragic birth of drug regulation -- The official manual of drug hunting: pharmacology becomes a science -- Beyond Salvarsan: the library of dirty medicine -- The pig elixir: the library of genetic medicine -- From blue death to beta blockers: the library of epidemiological medicine -- The pill: drug hunters striking gold outside of Big Pharma -- Mystery cures: discovering drugs through blind luck -- Conclusion: The future of the drug hunter: the Chevy Volt and the Lone Ranger.

"The surprising, behind-the-scenes story of how our medicines are discovered, told by a veteran drug hunter. The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity-- by chewing, brewing, and snorting--some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Otzi the Iceman, the five-thousand-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze-age medicine, a worm-killing birch fungus, knotted to his leggings. Nowadays, Big Pharma conglomerates spend billions of dollars on state-of the art laboratories staffed by PhDs to discover blockbuster drugs. Yet, despite our best efforts to engineer cures, luck, trial-and-error, risk, and ingenuity are still fundamental to medical discovery. Drug Hunters is a colorful, fact-filled narrative history of the search for new medicines from our Neolithic forebears to the professionals of today, and from quinine and aspirin to Viagra, Prozac, and Lipitor. The chapters offer a lively tour of how new drugs are actually found, the discovery strategies, the mistakes, and the rare successes. Dr. Donald R. Kirsch infuses the book with his own expertise and experiences from thirty-five years of drug hunting, whether searching for life-saving molecules in mudflats by Chesapeake Bay or as a chief science officer and research group leader at major pharmaceutical companies"-- Provided by publisher.

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