The end of Alzheimer's : the first program to prevent and reverse cognitive decline / Dale E. Bredesen, MD.

Includes bibliographical references (pages 295-298) and index.

Part one: The Alzheimer's solution. Disrupting dementia ; Patient zero ; How does it feel to come back from dementia? ; How to give yourself Alzheimer's : a primer -- Part two: Deconstructing Alzheimer's. Wit's end : from bedside to bench and back ; The God gene and the three types of Alzheimer's disease -- Part three: Evaluation and personalized therapeutics. The "cognoscopy" : where do you stand? ; ReCODE : reversing cognitive decline ; Success and the social network : two people's daily routines ; Putting it all together : you can do it ; This is not easy : workarounds and crutches ; Resistance to change : Machiavelli meets Feynman.

In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, this outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene.

"We fear Alzheimer's as we fear no other disease for two reasons. It is the only all one of the nation's ten most common causes of death for which there has been no effective treatment. And it is not only fatal: it robs its victims of their lives long before they are gone. But Dale E. Bredesen, MD, has turned the tables, showing that Alzheimer's disease and cognitive decline can not only be prevented but, in many cases, reversed. Now, in this paradigm-shifting book, he brings hope, and the first good news, to Alzheimer's patients, with a new understanding of the disease and a new program they can put into effect themselves. Dr. Bredesen reveals that Alzheimer's is not one condition, as it is currently treated, but several. They are driven by different mechanisms and typically manifest in different ways and at different ages. But all are dramatically influenced by imbalances in thirty-six metabolic factors that can trigger "downsizing" in the brain. He then explains his research-based protocol, which addresses ways to rebalance these mechanisms by adjusting lifestyle factors; including micronutrients, hormone levels. stress, and sleep quality. He explores the critical role of diet in cognitive decline as well as the importance of autophagy, which involves a strict overnight fast. The results have been impressive. Of the first ten patients on the protocol, nine displayed significant improvement within three to six months; since then the protocol has yielded similar results with hundreds more. With wide-ranging patient stories that allow us to understand what it's like to recover when recovery is deemed impossible, and specific information that will help patients, caregivers, physicians, and treatment centers put the protocol into action, this book will fundamentally change how we treat, prevent, and even think about Alzheimer's disease."--Jacket.