The lake house [text (large print)] : a novel / by James Patterson.

Enhanced descriptions from Syndetics:

Six kids on the run must face a villain who threatens the future of human existence . . . but winning comes at a high price.
Six children have escaped horrifying government experiments, a childhood in captivity, and a frightening brush with death. Living out in the world for the first time, they yearn to be reunited with Kit and Frannie, the couple who saved their lives. And Max, the leader of the flock, is seized by an overpowering fear that the kids are about to face a danger greater than any they've ever known.
All that the children want is to return to the one place they have ever felt truly protected: the waterfront cabin known as the Lake House. But in order to get there, they must thwart the sinister plans of a survivor from their worst nightmare -- plans that not only keep Kit, Frannie, and the children in constant peril, but threaten the future of human existence. And it's a battle they must be willing to pay any price to win.