000			03611cam a2200361Ii 4500
001			on1060524449
003			OCoLC
005			20181203021420.0
008			181101s2018 nyuaf e b 001 0 eng d
040			_aFMG _beng _erda _cFMG _dPCX _dQQ3 _dOCLCO _dIK2 _dOQX _dGL4 _dIMT _dVP@ _dNHP _dHQD _dBDX _dORK _dCZA _dVHP _dUAP _dIGA _dNFG
019			_a1057735066
020			_a9781455568505 _q(hardcover)
020			_a1455568503 _q(hardcover)
035			_a(OCoLC)1060524449 _z(OCoLC)1057735066
037			_bGrand Central Pub, C/O Little Brown & Co Order Dept 53 State st 9th Fl, Boston, MA, USA, 02109 _nSAN 200-2205
092			_a616.994 _bG734
049			_aNFGA
100	1		_aGraeber, Charles, _eauthor. _9228062
245	1	4	_aThe breakthrough : _bimmunotherapy and the race to cure cancer / _cCharles Graeber.
250			_aFirst edition.
264		1	_aNew York : _bTwelve, _c2018.
300			_a302 pages, 8 unnumbered pages of plates : _billustrations (chiefly color) ; _c24 cm
336			_atext _btxt _2rdacontent
337			_aunmediated _bn _2rdamedia
338			_avolume _bnc _2rdacarrier
504			_aIncludes bibliographical references (page 227-288) and index.
505	0		_aPatient 101006 JDS -- A simple idea -- Glimmers in the darkness -- Eureka, Texas -- The three E's -- Tempting fate -- The chimera -- After the gold rush -- It's time -- Appendix A: Types of immunotherapies now and upcoming -- Appendix B: The breakthrough, in brief -- Appendix C: A brief anecdotal history of disease, civilization, and the quest for immunity.
520			_aDraws on the experiences of patients, physicians, and researchers to explain the revolutionary development of immunotherapy as a treatment for cancer and how that information is being harnessed to create more effective patient therapies.
520			_a"For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses--tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it. In THE BREAKTHROUGH, Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step--harnessing the wealth of new information to create modern and more effective patient therapies--is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease. Groundbreaking, riveting, and expertly told, THE BREAKTHROUGH is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history"--Dust jacket.
650		0	_aCancer _xAlternative treatment. _9101602
650		0	_aCancer _xImmunotherapy. _9379335
994			_aC0 _bNFG
999			_c281064 _d281064