000 03120cam a2200409 i 4500
001 on1089516775
003 OCoLC
005 20200504131114.0
008 190611t20202020nyu b 001 0aeng
010 _a 2019020177
040 _aDLC
_beng
_erda
_cDLC
_dOCLCF
_dOCLCO
_dOCL
_dGK8
_dOQX
_dUAP
_dYDX
_dNFG
019 _a1140384527
020 _a9781541699069
_qhardcover
020 _a1541699068
_qhardcover
035 _a(OCoLC)1089516775
_z(OCoLC)1140384527
042 _apcc
092 _a571.86
_bZ58
049 _aNFGA
100 1 _aZernicka-Goetz, Magdalena,
_eauthor.
245 1 4 _aThe dance of life :
_bthe new science of how a single cell becomes a human being /
_cMagdalena Zernicka-Goetz and Roger Highfield.
250 _aFirst edition.
264 1 _aNew York :
_bBasic Books,
_c2020.
264 4 _c©2020
300 _avii, 289 pages ;
_c25 cm
336 _atext
_btxt
_2rdacontent
337 _aunmediated
_bn
_2rdamedia
338 _avolume
_bnc
_2rdacarrier
504 _aIncludes bibliographical references (pages 235-272) and index.
520 _a"Embryologist Magdalena Zernicka-Goetz has spent two decades unraveling the mysteries of fetal development. By studying embryonic mouse cells, she witnessed the embryo's ability to rid itself of abnormal cells as it prepared for implantation in the womb. When Zernicka-Goetz became pregnant at 44, she received a call that took her by surprise: a sample test of the cells in her own placenta indicated that the fetus had trisomy-2, a disastrous extra copy of the second chromosome, which increased the risk of miscarriage or serious birth defects. It seemed likely that the best choice was to have an abortion. But the plasticity of the embryonic mouse cells in her studies gave her hope; if mouse cells were able to course correct, then perhaps human cells were capable of similar resiliency. Six months later, she gave birth to a healthy baby boy, and the experience inspired her to begin a series of studies to test this hypothesis. Her subsequent experiments with early human embryos and artificial "three parent" embryos were not only groundbreaking; they also proved that embryotic cells could be artificially nurtured through the trials and tribulations of their early development. To say that her work is controversial would be an understatement, but as Zernicka-Goetz notes, harm can arise as much from doing nothing as from taking risks. And with profound implications for stem cell research, infertility treatment, prenatal diagnostic testing, immunotherapy, and genetic engineering, not to mention women's reproductive health, the stakes have never been higher. At once thought-provoking and thoroughly moving, The Dance of Life sheds new light on how a simple fertilized egg becomes a complex human being"--
_cProvided by publisher.
600 1 0 _aZernicka-Goetz, Magdalena.
650 0 _aEmbryologists
_vBiography.
650 0 _aFetus
_xDevelopment
_xResearch.
650 0 _aEmbryonic stem cells
_xResearch.
_9142664
655 7 _aAutobiographies.
_2lcgft
_9728
700 1 _aHighfield, Roger,
_eauthor.
_964822
994 _aC0
_bNFG
999 _c304650
_d304650